I'm fascinated by Geoge Church's personal genome project (the name recalls another PGP), in which one volunteers to have one's genome sequenced and made available for research. Personally, I think it's a great thing and I would be delighted to participate. I can't imagine caring if I (or the world) know that I have the gene for obsessive-compulsive disorder or whatever I may turn out to have. The one thing that gives me pause is wondering whether my children or siblings should have a say in whether I publish my genome, given that they share a fair bit of it. (I don't think my parents would mind.) The PGP web site doesn't discuss that issue, although it does point out other dangers that hadn't occurred to me, e.g.:
[someone might] make synthetic DNA corresponding to the participant and plant it at a crime scene
A quick search didn't reveal too many profound thoughts on this topic, just some recognition that if is an issue. E.g., from Baylor College of Medicine:
With [personal genomes] will come a host of legal and ethical issues, said Amy McGuire, J.D., Ph.D., Assistant Professor of Medicine in BCM's Center for Medical Ethics and Health Policy.
"Sequencing a personal genome possibly will reveal information about children, parents and siblings," she said. At present, there are no real standards as to what control family members can have over sequencing of an individual's genome or its release.
And some thoughts on the opposite dimension--a physician's "duty to warn.'